1,757 research outputs found
A transformation of business process models into software-executable models using MDA
Traditional software development projects for process-oriented organizations are time consuming and do not always guarantee the
fulfillment of the functional requirements of the client organization, and thus the quality of the resulting software product. To reduce the time
spent for developing software and improve its quality, we adopt the inclusion of automation in some parts of the software development process.
Thus, in this paper, we propose a model transformation approach to derive an executable model for the business processes of a given organization. We execute a mapping between processes (described with a business process execution language) and software components. We also propose a supporting software architecture based on an Enterprise Service Bus and on Java Business Integration, and we use an already defined methodology to execute the model transformation project.FEDER, FC
Early socialization and environmental enrichment of lactating piglets affects the caecal microbiota and metabolomic response after weaning
The aim of this study was to determine the possible impact of early socialization and an enriched neonatal environment to improve adaptation of piglets to weaning. We hypothesized that changes in the microbiota colonization process and in their metabolic response and intestinal functionality could help the animals face weaning stress. A total of 48 sows and their litters were allotted into a control (CTR) or an enriched treatment (ENR), in which piglets from two adjacent pens were combined and enriched with toys. The pattern of caecal microbial colonization, the jejunal gene expression, the serum metabolome and the intestinal physiology of the piglets were assessed before (-2 d) and after weaning (+ 3d). A differential ordination of caecal microbiota was observed after weaning. Serum metabolome suggested a reduced energetic metabolism in ENR animals, as evidenced by shifts in triglycerides and fatty acids, VLDL/LDL and creatine regions. The TLR2 gene showed to be downregulated in the jejunum of ENR pigs after weaning. The integration of gene expression, metabolome and microbiota datasets confirmed that differences between barren and enriched neonatal environments were evident only after weaning. Our results suggest that improvements in adaptation to weaning could be mediated by a better response to the post-weaning stress.info:eu-repo/semantics/publishedVersio
CP--violating Chargino Contributions to the Higgs Coupling to Photon Pairs in the Decoupling Regime of Higgs Sector
In most supersymmetric theories, charginos belong to
the class of the lightest supersymmetric particles and the couplings of Higgs
bosons to charginos are in general complex so that the CP--violating chargino
contributions to the loop--induced coupling of the lightest Higgs boson to
photon pairs can be sizable even in the decoupling limit of large pseudoscalar
mass with only the lightest Higgs boson kinematically accessible at
future high energy colliders. We introduce a specific benchmark scenario of CP
violation consistent with the electric dipole moment constraints and with a
commonly accepted baryogenesis mechanism in the minimal supersymmetric Standard
Model. Based on the benchmark scenario of CP violation, we demonstrate that the
fusion of the lightest Higgs boson in linearly polarized photon--photon
collisions can allow us to confirm the existence of the CP--violating chargino
contributions {\it even in the decoupling regime of the Higgs sector} for
nearly degenerate SU(2) gaugino and higgsino mass parameters of about the
electroweak scale.Comment: 1+13 pages, 3 eps figure
MSSM Higgs sector CP violation at photon colliders: Revisited
We present a comprehensive analysis on the MSSM Higgs sector CP violation at
photon colliders including the chargino contributions as well as the
contributions of other charged particles. The chargino loop contributions can
be important for the would-be CP odd Higgs production at photon colliders.
Polarization asymmetries are indispensable in determining the CP properties of
neutral Higgs bosons.Comment: 24 pages, 40 figure
Reducing overuse of cervical cancer screening: A systematic review
Overuse of clinical preventive services increases healthcare costs and may deprive underserved patients of necessary care. Up to 45% of cervical cancer screening is overuse. We conducted a systematic review of correlates of overuse of cervical cancer screening and interventions to reduce overuse. The search identified 25 studies (20 observational; 5 intervention). Correlates varied by the type of overuse measured (i.e., too frequent, before/after recommended age to start or stop screening, after hysterectomy), the most common correlates of overuse related to patient age (n = 7), OBGYN practice or provider (n = 5), location (n = 4), and marital status (n = 4). Six observational studies reported a decrease in overuse over time. Screening overuse decreased in all intervention studies, which used before-after designs with no control or comparison groups. Observational studies suggest potential targets for de-escalating overuse. Randomized clinical trials are needed to establish best practices for reducing overuse
Strong Couplings of Heavy Mesons to A Light Vector Meson in QCD
We make a detailed analysis of the and
strong couplings and
using QCD light cone sum rules(LCSR). The
existing some negligence is pointed out in the previous LCSR calculation on
) and an updated estimate is presented. Our
findings can be used to understand the behavior of the
semileptonic form factors at large momentum transitions.Comment: 15 pages, latex, 2 figures, version appearing in PRD, typos correcte
Simulations of the Static Friction Due to Adsorbed Molecules
The static friction between crystalline surfaces separated by a molecularly
thin layer of adsorbed molecules is calculated using molecular dynamics
simulations. These molecules naturally lead to a finite static friction that is
consistent with macroscopic friction laws. Crystalline alignment, sliding
direction, and the number of adsorbed molecules are not controlled in most
experiments and are shown to have little effect on the friction. Temperature,
molecular geometry and interaction potentials can have larger effects on
friction. The observed trends in friction can be understood in terms of a
simple hard sphere model.Comment: 13 pages, 13 figure
Coronary Atherosclerosis Phenotypes in Focal and Diffuse Disease.
The interplay between coronary hemodynamics and plaque characteristics remains poorly understood.
The aim of this study was to compare atherosclerotic plaque phenotypes between focal and diffuse coronary artery disease (CAD) defined by coronary hemodynamics.
This multicenter, prospective, single-arm study was conducted in 5 countries. Patients with functionally significant lesions based on an invasive fractional flow reserve ≤0.80 were included. Plaque analysis was performed by using coronary computed tomography angiography and optical coherence tomography. CAD patterns were assessed using motorized fractional flow reserve pullbacks and quantified by pullback pressure gradient (PPG). Focal and diffuse CAD was defined according to the median PPG value.
A total of 117 patients (120 vessels) were included. The median PPG was 0.66 (IQR: 0.54-0.75). According to coronary computed tomography angiography analysis, plaque burden was higher in patients with focal CAD (87% ± 8% focal vs 82% ± 10% diffuse; P = 0.003). Calcifications were significantly more prevalent in patients with diffuse CAD (Agatston score per vessel: 51 [IQR: 11-204] focal vs 158 [IQR: 52-341] diffuse; P = 0.024). According to optical coherence tomography analysis, patients with focal CAD had a significantly higher prevalence of circumferential lipid-rich plaque (37% focal vs 4% diffuse; P = 0.001) and thin-cap fibroatheroma (TCFA) (47% focal vs 10% diffuse; P = 0.002). Focal disease defined by PPG predicted the presence of TCFA with an area under the curve of 0.73 (95% CI: 0.58-0.87).
Atherosclerotic plaque phenotypes associate with intracoronary hemodynamics. Focal CAD had a higher plaque burden and was predominantly lipid-rich with a high prevalence of TCFA, whereas calcifications were more prevalent in diffuse CAD. (Precise Percutaneous Coronary Intervention Plan [P3]; NCT03782688)
Search for and Using Genetic Programming Event Selection
We apply a genetic programming technique to search for the double Cabibbo
suppressed decays and .
We normalize these decays to their Cabibbo favored partners and find
\Lambda_c^+ \to p K^+ \pi^-\Lambda_c^+ \to p K^-
\pi^+ and D_s^+ \to K^+ K^+
\pi^-D_s^+ \to K^+ K^- \pi^+ where
the first errors are statistical and the second are systematic. Expressed as
90% confidence levels (CL), we find and respectively.
This is the first successful use of genetic programming in a high energy
physics data analysis.Comment: 10 page
- …